Key points
- Staging of myeloma helps to determine the extent of the disease and informs assessment of the likely prognosis
- The R-ISS stages myeloma based on the following four factors:
- β2M
- Albumin
- Presence or absence of high-risk chromosomal abnormalities
- LDH
- Staging myeloma together with other prognostic factors allows patients to be risk stratified. This can help give patients some idea of their prognosis and may help guide treatment decisions.
- The prognosis of myeloma is an area of ongoing research and will continue to advance rapidly in the near future.