Other consolidation and maintenance options

The one licensed consolidation option in the UK is daratumumab in combination with bortezomib, thalidomide and dexamethasone (DVTD). Two cycles can be given following stem cell transplantation and prior to lenalidomide maintenance, in transplant eligible patients. Several other treatment combinations are being investigated and are available in clinical trials.

Further reading

Sonneveld et al. (2021) Consolidation and Maintenance in Newly Diagnosed Multiple Myeloma. J Clin Onc. doi: 10.1200/JCO.21.01045.

Dimopolous et al. (2020) Developments in continuous therapy and maintenance treatment approaches for patients with newly diagnosed multiple myeloma. Blood Cancer Journal volume 10, Article number: 17