IMWG consensus guidelines and recommendations for infection prevention in myeloma

Infection remains the leading cause of morbidity and mortality among patients with multiple myeloma, primarily due to the cumulative effects of the disease, its treatments, and host-related factors. As the risk of infections escalates throughout the course of myeloma, effective prevention strategies are paramount.

The guidelines encompass key strategies such as vaccination against common pathogens, antimicrobial prophylaxis, rigorous infection control measures, and immunoglobulin replacement for a select subset of patients. Despite the wealth of knowledge and best practices, the absence of universally accepted guidelines for infection prevention underscores the need for personalised approaches tailored to individual patient circumstances.

The article not only summarises current literature and guidelines but also addresses the challenges posed by emerging therapies and their impact on infection risk management. By outlining evidence-based recommendations, this report aims to enhance patient safety and reduce the incidence of infectious complications in individuals living with myeloma.

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  • IMWG

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